Chapter 1 - Purpose and Background

A. Purpose

The medical grounds of inadmissibility, the medical examination of aliens, and the vaccinations administered to aliens are designed to protect the health of the United States population. The immigration medical examination, the resulting medical examination report, and the vaccination record provide the information USCIS uses to determine if an alien meets the health-related standards for admissibility.

Four basic medical conditions may make an applicant inadmissible on health-related grounds:

  • Communicable disease of public health significance,

  • Failure to show proof of required vaccinations,

  • Physical or mental disorder with associated harmful behavior, and

  • Drug abuse or addiction.

B. Background

Public health concerns have been reflected in U.S. immigration law since the Immigration Act of 1882.[1] Among others, “persons suffering from a loathsome or a dangerous contagious disease” were not allowed to enter the United States.[2] In 1990, Congress revised and consolidated all of the grounds of inadmissibility. It narrowed health-related grounds of inadmissibility to include only aliens with communicable diseases, physical or mental disorders with associated harmful behavior, or those with drug abuse or addiction problems.[3] 

As of 1996, Congress requires all immigrant visa and adjustment of status applicants to establish that they have been vaccinated against certain vaccine-preventable diseases.[4] 

C. Role of the Department of Health and Human Services (HHS)

Because medical knowledge and public health concerns can and do change over time, Congress gave the Department of Health and Human Services (HHS) the authority to designate by regulations which conditions make a person inadmissible on health-related grounds. 

The HHS component charged with defining these medical conditions is the Centers for Disease Control and Prevention (CDC). CDC’s responsibilities include:

  • Publishing regulations addressing health-related conditions that render an applicant inadmissible;

  • Establishing the medical examination requirements in its Technical Instructions for Medical Examination of Aliens (Technical Instructions) that are binding on civil surgeons in the United States, panel physicians overseas, USCIS officers, and State Department consular officers;[5] 

  • Responding to medical questions that officers, civil surgeons, and panel physicians may have based on the Technical Instructions;[6] and

  • Advising USCIS on the adjudication of medical waivers.

D. Role of the Department of Homeland Security (DHS)

Congress authorizes the Department of Homeland Security (DHS) to determine an alien’s admissibility to the United States, which includes determinations based on health reasons.[7] DHS must follow HHS regulations and instructions when determining whether an applicant is inadmissible on health-related grounds.[8] 

Congress also empowers DHS to designate qualified physicians as civil surgeons who conduct medical examinations of aliens physically present in the United States.[9] 

E. Making a Health-Related Inadmissibility Determination

To make a health-related inadmissibility determination, the officer should follow the steps outlined below: 

Overview of Process of Making a Health-Related Inadmissibility Determination

Step of Adjudication

Where can I find 
​on this step? 

Step 1: Is the applicant subject to the health-related grounds of inadmissibility or is there another reason that requires the applicant to undergo an immigration medical examination? 

Chapter 3, Applicability of Medical Examination and Vaccination Requirement [8 USCIS-PM B.3]

Step 2: If required, has the applicant been medically examined by the appropriate physician and is the appropriate medical documentation in the file? 

Chapter 3, Applicability of Medical Examinationand Vaccination Requirement [8 USCIS-PM B.3]

Step 3: Was the medical documentation[10] properly completed and is it still valid?

Chapter 4, Review of Medical Examination Documentation [8 USCIS-PM B.4] through Chapter 10, Other Medical Conditions [8 USCIS-PM B.10]

Step 4: Is the applicant inadmissible based on the health-related grounds?

Chapter 11, Inadmissibility Determination [8 USCIS-PM B.11]

Step 5: Is the applicant inadmissible based on grounds other than the health-related grounds, as evidenced by the medical documentation?

Chapter 11, Inadmissibility Determination, Section D, Other Grounds of Inadmissibility [8 USCIS-PM B.11(D)]

F. Legal Authorities

  • INA 212(a)(1) – Health-related grounds

  • INA 221(d) – Physical examination

  • INA 2328 CFR 232 – Detention of aliens for physical and mental examination

  • 42 U.S.C. 252 – Medical examination of aliens

  • 42 CFR 34 – Medical examination of aliens

  • Technical Instructions for Civil Surgeons (Technical Instructions), and updates[11] 


1. [^] See the Immigration Act of 1882, 22 Stat. 214 (August 3, 1882).

2. [^] See the Immigration Act of 1891, 26 Stat. 1084 (March 3, 1891). 

3. [^] See the Immigration Act of 1990 (IMMACT 90), Pub. L. 101-649 (PDF) (November 29, 1990).

4. [^] See the Illegal Immigration Reform and Immigrant Responsibility Act of 1996 (IIRIRA), Division C of Pub. L. 104-208 (PDF) (September 30, 1996). See INA 212(a)(1)(A)(ii).

5. [^] Officers and designated physicians must obtain the Technical Instructions from CDC’s website at Updates to the Technical Instructions must also be followed.

6. [^] CDC can be reached at Officers should identify themselves as an immigration officer in the e-mail. This e-mail address is not for inquiries from the public. It is only for inquiries from immigration officers and civil surgeons. Inquiries from the public should be submitted to CDC INFO at

7. [^] See INA 212(a).

8. [^] See INA 212(a)(1)(A).

9. [^] See INA 232.

10. [^] Medical documentation refers to the following: Report of Medical Examination and Vaccination Record (Form I-693), Report of Medical Examination by Panel Physician (Form DS-2054), and any other related worksheets.

11. [^] Available online at

42 CFR 34 - Medical examination of aliens

42 U.S.C. 252 - Medical examination of aliens

INA 212(a)(1) - Health-related grounds

INA 221(d) - Physical examination

INA 232, 8 CFR 232 - Detention of aliens for physical and mental examination


No appendices available at this time.

Technical Update - Moving the Adjudicator’s Field Manual Content into the USCIS Policy Manual

May 21, 2020

U.S. Citizenship and Immigration Services (USCIS) is updating and incorporating relevant Adjudicator’s Field Manual (AFM) content into the USCIS Policy Manual. As that process is ongoing, USCIS has moved any remaining AFM content to its corresponding USCIS Policy Manual Part, in PDF format, until relevant AFM content has been properly incorporated into the USCIS Policy Manual. To the extent that a provision in the USCIS Policy Manual conflicts with remaining AFM content or Policy Memoranda, the updated information in the USCIS Policy Manual prevails. To find remaining AFM content, see the crosswalk between the AFM and the Policy Manual.



Technical Update - Health-Related Grounds of Inadmissibility

December 10, 2019

U.S. Citizenship and Immigration Services (USCIS) is updating existing guidance based on revised Centers for Disease Control and Prevention Technical Instructions regarding tuberculosis, gonorrhea, and syphilis and the change in nomenclature from leprosy to Hansen’s Disease. USCIS is also updating how USCIS submits a request to CDC for advisory opinion and removing the outdated vaccination chart.



Technical Update - Replacing the Term “Foreign National”

October 08, 2019

This technical update replaces all instances of the term “foreign national” with “alien” throughout the Policy Manual as used to refer to a person who meets the definition provided in INA 101(a)(3) [“any person not a citizen or national of the United States”].



POLICY ALERT - Validity of Report of Medical Examination and Vaccination Record (Form I-693)

October 16, 2018

U.S. Citizenship and Immigration Services (USCIS) is updating policy guidance in Volume 8, Part B of the USCIS Policy Manual regarding the period of time during which a Form I-693 submitted in support of a related immigration benefits application is considered valid.



POLICY ALERT - Definition of Certain Classes of Medical Conditions and Other Updates Relating to Health-Related Grounds of Inadmissibility

November 02, 2016

U.S. Citizenship and Immigration Services (USCIS) is updating guidance regarding health-related grounds of inadmissibility in accordance with the U.S. Department of Health and Human Services (HHS) rulemaking updating Title 42 of the Code of Federal Regulations, part 34 (42 CFR 34).



POLICY ALERT - Health-Related Grounds of Inadmissibility and Waivers

January 28, 2014

U.S. Citizenship and Immigration Services (USCIS) is issuing guidance in the USCIS Policy Manual on the health-related grounds of inadmissibility under INA 212(a)(1) and corresponding waivers under INA 212(g).


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